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Post-organ transplantation, patients must consume immunosuppressant drugs such as corticosteroids, calcineurin inhibitors, or monoclonal antibodies to facilitate graft acceptance.
As with any transplantation, the immune system inherently recognises the organ as a foreign object before attacking and rejecting it.
Immunosuppressant medication weakens the immune system enough to reduce the body’s reaction to the allograft and promote cytokine release.